Hironobu Sasano Selected Research

Adrenocortical Carcinoma

1/2024	Histopathological analysis of tumor microenvironment in adrenocortical carcinoma: Possible effects of in situ disorganized glucocorticoid production on tumor immunity.
12/2023	Challenges in the diagnosis of the enigmatic primary adrenal leiomyosarcoma: two case reports and review of the literature.
1/2022	Visualization of calcium channel blockers in human adrenal tissues and their possible effects on steroidogenesis in the patients with primary aldosteronism (PA).
11/2021	Oncocytic Adrenocortical Carcinoma With Low 18F-FDG Uptake and the Absence of Glucose Transporter 1 Expression.
10/2021	Carcinoma of unknown primary origin with isolated adrenal metastasis: a report of two cases.
1/2021	Data set for reporting of carcinoma of the adrenal cortex: explanations and recommendations of the guidelines from the International Collaboration on Cancer Reporting.
1/2021	Adrenal and Hepatic Venous Sampling in a Case of Aldosterone-Producing Adrenocortical Carcinoma with Hepatic Metastasis.
11/2020	Steroid metabolites for diagnosing and predicting clinicopathological features in cortisol-producing adrenocortical carcinoma.
1/2020	CCNB2 and AURKA overexpression may cause atypical mitosis in Japanese cortisol-producing adrenocortical carcinoma with TP53 somatic variant.
6/2018	Immunohistochemical Biomarkers of Adrenal Cortical Neoplasms.

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Hironobu Sasano Research Topics

Disease

284	Neoplasms (Cancer) 01/2024 - 01/2000
186	Breast Neoplasms (Breast Cancer) 12/2023 - 01/2002
94	Carcinoma (Carcinomatosis) 10/2023 - 01/2000
85	Adenoma (Adenomas) 04/2024 - 03/2002
65	Hyperaldosteronism (Conn Syndrome) 03/2024 - 03/2002
35	Neoplasm Metastasis (Metastasis) 12/2023 - 01/2000
32	Cushing Syndrome 07/2021 - 07/2002
30	Hyperplasia 09/2021 - 03/2002
26	Adrenocortical Adenoma (Disease, Conn's) 01/2024 - 08/2003
25	Adrenocortical Carcinoma 01/2024 - 04/2006
25	Hypertension (High Blood Pressure) 10/2023 - 07/2002
19	Ductal Carcinoma 06/2022 - 02/2004
17	Neuroendocrine Tumors (Neuroendocrine Tumor) 11/2023 - 07/2007
17	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023 - 07/2005
17	Noninfiltrating Intraductal Carcinoma (DCIS) 09/2018 - 03/2006
16	Pheochromocytoma 09/2023 - 01/2000
16	Endometrial Neoplasms (Endometrial Cancer) 03/2022 - 06/2002
15	Triple Negative Breast Neoplasms 11/2023 - 05/2013
14	Lung Neoplasms (Lung Cancer) 12/2023 - 07/2011
14	Lymphatic Metastasis 01/2022 - 02/2004
13	Adenocarcinoma 06/2020 - 06/2002
12	Adenocarcinoma of Lung 01/2022 - 08/2010
11	Esophageal Squamous Cell Carcinoma 06/2022 - 02/2010
11	Hypokalemia 09/2020 - 03/2002
11	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 07/2004
9	Squamous Cell Carcinoma (Epidermoid Carcinoma) 05/2023 - 09/2003
9	Carcinogenesis 11/2022 - 01/2000
9	Ovarian Neoplasms (Ovarian Cancer) 02/2019 - 07/2002
9	Ovarian Epithelial Carcinoma 05/2010 - 07/2002
8	Hepatocellular Carcinoma (Hepatoma) 10/2021 - 08/2002
7	Disease Progression 01/2021 - 01/2005
7	Acth-Independent Macronodular Adrenal Hyperplasia 09/2017 - 04/2002
6	Obesity 01/2022 - 01/2013
6	Inflammation (Inflammations) 06/2020 - 02/2002
6	Fibrosis (Cirrhosis) 12/2019 - 01/2003

Drug/Important Bio-Agent (IBA)

120	Estrogens (Estrogen)FDA Link 03/2022 - 01/2002
102	AldosteroneIBA 04/2024 - 03/2002
93	EnzymesIBA 03/2024 - 01/2002
81	Estrogen ReceptorsIBA 06/2023 - 02/2004
70	SteroidsIBA 05/2023 - 01/2002
67	Messenger RNA (mRNA)IBA 01/2022 - 03/2002
66	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2024 - 04/2002
64	Proteins (Proteins, Gene)FDA Link 01/2024 - 02/2002
63	Aromatase (CYP19)IBA 04/2021 - 01/2002
62	Hormones (Hormone)IBA 12/2023 - 01/2003
61	AndrogensIBA 11/2023 - 06/2002
41	Aromatase InhibitorsIBA 08/2021 - 09/2003
38	Progesterone Receptors (Progesterone Receptor)IBA 01/2023 - 07/2002
34	Biomarkers (Surrogate Marker)IBA 05/2023 - 09/2005
32	Adrenocorticotropic Hormone (ACTH)FDA Link 12/2022 - 03/2002
28	Cytochrome P-450 CYP11B2 (CYP11B2)IBA 01/2024 - 08/2004
28	Androgen Receptors (Androgen Receptor)IBA 11/2023 - 06/2002
26	Oxidoreductases (Dehydrogenase)IBA 01/2023 - 04/2005
20	Estradiol (Delestrogen)FDA LinkGeneric 03/2021 - 05/2003
20	Steryl-Sulfatase (Steroid Sulfatase)IBA 01/2021 - 01/2002
17	ReninIBA 03/2024 - 03/2002
17	GlucocorticoidsIBA 01/2024 - 01/2003
16	ErbB Receptors (EGF Receptor)IBA 08/2022 - 12/2008
15	3 (or 17)-beta-hydroxysteroid dehydrogenaseIBA 06/2010 - 01/2002
14	Progesterone FDA LinkGeneric 12/2023 - 07/2002
14	Estrogen Receptor alphaIBA 01/2017 - 05/2003
13	LigandsIBA 11/2022 - 07/2006
13	Estrogen Receptor betaIBA 01/2017 - 03/2004
12	Dehydroepiandrosterone (DHEA)IBA 01/2023 - 09/2003
12	Protein Isoforms (Isoforms)IBA 01/2023 - 05/2002
11	Tamoxifen FDA LinkGeneric 06/2022 - 07/2004
11	LipidsIBA 01/2022 - 05/2009
11	estrone sulfotransferaseIBA 01/2021 - 01/2002
10	MicroRNAs (MicroRNA)IBA 01/2023 - 01/2010
10	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 02/2022 - 07/2007
10	Phenobarbital (Luminal)FDA Link 12/2021 - 03/2006
10	Transcription Factors (Transcription Factor)IBA 07/2021 - 09/2003
9	CytokinesIBA 09/2023 - 01/2008
9	Formaldehyde (Formol)FDA Link 12/2021 - 09/2005
9	ParaffinIBA 12/2021 - 01/2004
9	Tyrosine Kinase InhibitorsIBA 08/2021 - 10/2014
9	exemestane (Aromasin)FDA Link 09/2019 - 06/2010
9	Steroid Receptors (Steroid Receptor)IBA 01/2019 - 05/2003
9	Testosterone (Sustanon)FDA Link 01/2017 - 06/2002
8	Steroid 11-beta-Hydroxylase (11 beta-Hydroxylase)IBA 01/2024 - 07/2014
8	CatecholaminesIBA 09/2023 - 01/2016
8	Monoclonal AntibodiesIBA 08/2022 - 05/2005
8	Estrone FDA Link 05/2011 - 05/2003
7	VimentinIBA 12/2023 - 11/2006
7	PotassiumIBA 11/2022 - 07/2002
7	DNA (Deoxyribonucleic Acid)IBA 06/2022 - 10/2007
7	human ERBB2 proteinIBA 12/2021 - 03/2012
7	11-beta-Hydroxysteroid Dehydrogenase Type 2 (11 beta-Hydroxysteroid Dehydrogenase Type 2)IBA 01/2008 - 11/2002
6	Epidermal Growth Factor (EGF)IBA 12/2023 - 03/2008
6	SynaptophysinIBA 02/2023 - 03/2014
6	dehydroepiandrosterone sulfotransferaseIBA 01/2023 - 08/2003
6	Hydroxysteroid DehydrogenasesIBA 06/2022 - 04/2005
6	Trastuzumab (Herceptin)FDA Link 12/2021 - 10/2007
6	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 07/2006

Therapy/Procedure

112	Therapeutics 11/2023 - 06/2003
36	Adrenalectomy 09/2023 - 03/2002
21	Drug Therapy (Chemotherapy) 12/2023 - 01/2009
15	Neoadjuvant Therapy 06/2022 - 10/2005
14	Lasers (Laser) 01/2022 - 06/2003
6	Aftercare (After-Treatment) 05/2022 - 08/2007